Niacinamide: Long term safety studies have demonstrated that niacinamide may be safely supplemented at 3000mg (3g) per day (or night). During the day, you can apply a sunscreen that contains this power ingredient. It is more common in individuals who are 45 to 64 years of age and among people of all races. It is taken orally. However, there is evidence that niacinamide taken before going to bed can help you get to sleep, since it activates benzodiazepine receptors in the brain; a dose of 50 right up to 1,000 mg is recommended. Skin aging is a complex biological process influenced by a combination of endogenous or intrinsic and exogenous or extrinsic factors. Century Niacinamide 500 mg Prolonged Release Tablets, 110-Count In fact, many patients find that the flushing stops after 1 to 2 weeks of being on a … Retinol For Acne: Safety, Side Effects, Products - Healthline Dosages of 50 mg to 1,000 mg of niacinamide taken at bedtime have helped many people sleep better. In one 24-week trial, men with high lipoprotein saw declines in lipoprotein(a) levels when treated with high-dose, extended-release niacin. I'm so thankful to have found this product Oh, and the NOW brand is an excellent brand. Niacin for sleep | Phoenix Rising ME/CFS Forums